{"id":4420,"date":"2018-06-15T10:27:02","date_gmt":"2018-06-15T14:27:02","guid":{"rendered":"http:\/\/www.ipoboutique.com\/blog\/?p=4420"},"modified":"2018-06-15T10:27:02","modified_gmt":"2018-06-15T14:27:02","slug":"avrobio-inc-ipo-preview-avro","status":"publish","type":"post","link":"https:\/\/www.ipoboutique.com\/blog\/avrobio-inc-ipo-preview-avro\/","title":{"rendered":"AVROBIO, Inc. #IPO Preview ($AVRO)"},"content":{"rendered":"<p><a href=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/06\/AVRO.jpg\"><img decoding=\"async\" class=\"aligncenter size-full wp-image-4421\" src=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/06\/AVRO.jpg\" alt=\"AVRO\" width=\"181\" height=\"46\" \/><\/a><\/p>\n<p>Company: AVROBIO, Inc.<br \/>\nSymbol: AVRO<br \/>\nDescription: They are a clinical stage gene therapy company focused on developing potentially curative ex vivo lentiviral-based gene therapies to treat rare diseases following a single dose.<br \/>\nTrade Date: 6\/21<br \/>\nShares: 4.4 million<br \/>\nPrice Range: $16.00-$18.00<br \/>\nUnderwriter(s): Morgan Stanley, Cowen, Wells Fargo Securities<br \/>\nCo-Manager(s): Wedbush Pacgrow<br \/>\nTerms Added: 6-11-18<\/p>\n<p><strong><a href=\"https:\/\/www.sec.gov\/Archives\/edgar\/data\/1681087\/000119312518188630\/d562006ds1a.htm\" target=\"_blank\">Link to Prospectus<\/a><\/strong><\/p>\n<p><strong><a href=\"http:\/\/www.retailroadshow.com\/wp\/roadshows.asp\" target=\"_blank\">Link to Retail Roadshow<\/a><\/strong><\/p>\n<p><strong>Business<\/strong>:\u00a0They are a Phase\u00a02 clinical stage gene therapy company focused on developing potentially curative\u00a0ex vivo\u00a0lentiviral-based gene therapies to treat rare diseases following a single dose. Their gene therapies employ hematopoietic stem cells that are extracted from the patient and then modified with lentiviral vectors to insert a functional copy of the gene that is defective in the target disease. They believe that their approach, which transforms stem cells from patients into therapeutic products, has the potential to provide curative benefit for a range of diseases in an outpatient setting. Their initial focus is on a group of rare genetic diseases referred to as lysosomal storage diseases, which today are primarily managed with enzyme replacement therapies, or ERTs. These lysosomal storage diseases have well understood biologies, identified patient populations and represent large market opportunities with approximately $4.0\u00a0billion in worldwide net sales in 2017.<br \/>\n<a href=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/06\/AVRO.Pipeline.jpg\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-4422\" src=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/06\/AVRO.Pipeline.jpg\" alt=\"AVRO.Pipeline\" width=\"607\" height=\"315\" srcset=\"https:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/06\/AVRO.Pipeline.jpg 607w, https:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/06\/AVRO.Pipeline-600x311.jpg 600w, https:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/06\/AVRO.Pipeline-300x156.jpg 300w\" sizes=\"(max-width: 607px) 100vw, 607px\" \/><\/a><\/p>\n<p><strong>Insider Buying:<\/strong>\u00a0Certain of their\u00a0existing stockholders, including entities affiliated with certain of our directors, have indicated an interest in purchasing an aggregate of approximately $37.5 million in shares of their\u00a0common stock in this offering at the initial public offering price per share.<\/p>\n<p><strong>Book-Building Status<\/strong>: The way the book comes together during the week of the roadshow is the most critical indicator to first-day and first-week performance. IPO Boutique uses its 45 years of experience and sources all over the street to gather daily subscription levels, specific price guidance and what type of investors are currently in the book or are anchoring orders in the book. In addition, recent underwriter performance on sector specific deals is a strong factor that IPO Boutique takes into account when determining if our clients should indicate for any offering.<\/p>\n<p><a href=\"https:\/\/www.ipoboutique.com\/Subscribe.html\"><span style=\"font-weight: 400;\">IPO Boutique subscription clients receive daily updates on this critical information.<\/span><\/a><\/p>\n<p><strong>Conclusion<\/strong>: IPO Boutique provides ratings, daily commentary and a forecast for how this IPO will open vs. its offering price. We have kept a\u00a0<a href=\"https:\/\/www.ipoboutique.com\/cgi\/ipo-track-record-summary-report.php\"><span style=\"font-weight: 400;\">track record<\/span><\/a>\u00a0with our performance for last 12 years at our website. Additionally, here&#8217;s a<a href=\"http:\/\/www.ipoboutique.com\/blog\/?p=3655\"> 2017 recap of our performance<\/a>\u00a0to showcase the value of IPO Boutique&#8217;s service.<\/p>\n<p><b>Indicate with confidence,\u00a0<\/b><a href=\"https:\/\/www.ipoboutique.com\/Subscribe.html\"><b>SUBSCRIBE<\/b><\/a><b>\u00a0today.<\/b><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Company: AVROBIO, Inc. Symbol: AVRO Description: They are a clinical stage gene therapy company focused on developing potentially curative ex vivo lentiviral-based gene therapies to treat rare diseases following a single dose. Trade Date: 6\/21 Shares: 4.4 million Price Range: $16.00-$18.00 Underwriter(s): Morgan Stanley, Cowen, Wells Fargo Securities Co-Manager(s): Wedbush Pacgrow Terms Added: 6-11-18 Link[&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"zakra_general_container_width":0,"zakra_general_content_width":0,"zakra_general_sidebar_width":0,"zakra_sticky_header":"customizer","zakra_header_main_area":true,"zakra_site_logo_width":0,"zakra_header_top_enabled":"customizer","zakra_header_top_style":"customizer","zakra_primary_menu_item_style":"customizer","zakra_page_header_text_color":"","zakra_page_header_layout":"customizer","zakra_page_title_bg":"","zakra_footer_widgets_bg_image":0,"zakra_page_title_bg_repeat":"customizer","zakra_page_title_bg_position":"customizer","zakra_page_title_bg_size":"customizer","zakra_page_title_bg_attachment":"customizer","zakra_breadcrumbs_enabled":"customizer","zakra_breadcrumbs_text_color":"","zakra_breadcrumbs_separator_color":"","zakra_breadcrumbs_link_color":"","zakra_breadcrumbs_link_hover_color":"","zakra_page_title_bg_image":0,"zakra_footer_widgets_enabled":"customizer","zakra_footer_column_layout_1_style":"customizer","zakra_footer_widgets_bg":"","zakra_footer_widgets_bg_repeat":"customizer","zakra_footer_widgets_bg_position":"customizer","zakra_footer_widgets_bg_size":"customizer","zakra_footer_widgets_bg_attachment":"customizer","zakra_footer_bar_enabled":"customizer","zakra_footer_bar_style":"customizer","footnotes":""},"categories":[24],"tags":[1517],"class_list":["post-4420","post","type-post","status-publish","format-standard","hentry","category-ipo","tag-avro"],"_links":{"self":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts\/4420","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/comments?post=4420"}],"version-history":[{"count":1,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts\/4420\/revisions"}],"predecessor-version":[{"id":4423,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts\/4420\/revisions\/4423"}],"wp:attachment":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/media?parent=4420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/categories?post=4420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/tags?post=4420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}