{"id":4226,"date":"2018-04-27T10:27:58","date_gmt":"2018-04-27T14:27:58","guid":{"rendered":"http:\/\/www.ipoboutique.com\/blog\/?p=4226"},"modified":"2018-04-27T10:27:58","modified_gmt":"2018-04-27T14:27:58","slug":"unity-biotechnology-inc-ipo-preview-ubx","status":"publish","type":"post","link":"https:\/\/www.ipoboutique.com\/blog\/unity-biotechnology-inc-ipo-preview-ubx\/","title":{"rendered":"Unity Biotechnology, Inc. #IPO Preview ($UBX)"},"content":{"rendered":"<p><a href=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/04\/UBX.jpg\"><img decoding=\"async\" class=\"aligncenter size-full wp-image-4227\" src=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/04\/UBX.jpg\" alt=\"UBX\" width=\"214\" height=\"64\" \/><\/a><\/p>\n<p>Company: <strong>Unity Biotechnology, Inc.<\/strong><br \/>\nSymbol: UBX<br \/>\nDescription: They are looking to develop a broad portfolio of drug candidates to treat the diseases of aging, and they plan to initiate their first clinical study of their lead drug candidate in the first half of 2018.<br \/>\nTrade Date: 5\/3<br \/>\nShares: 5 million<br \/>\nPrice Range: $16.00-$18.00<br \/>\nUnderwriter(s): Goldman Sachs &amp; Co., Morgan Stanley, Citigroup<br \/>\nCo-Manager(s): Mizuho Securities<br \/>\nTerms Added: 4-23-18<\/p>\n<p><strong><a href=\"https:\/\/www.sec.gov\/Archives\/edgar\/data\/1463361\/000119312518125773\/d535851ds1a.htm\" target=\"_blank\">Link to Prospectus<\/a><\/strong><\/p>\n<p><strong><a href=\"http:\/\/www.retailroadshow.com\/wp\/roadshows.asp\" target=\"_blank\">Link to Retail Roadshow<\/a><\/strong><\/p>\n<p><strong>Business<\/strong>:\u00a0Enabled by foundational scientific insights, they have devoted over six years to identifying multiple mechanisms that they believe to be root causes of age-associated disease. They are utilizing these insights to develop a broad portfolio of drug candidates to treat these diseases of aging, and they plan to initiate their first clinical study of their lead drug candidate in the second quarter of 2018.<\/p>\n<p>UBX0101 is their\u00a0lead drug candidate for musculoskeletal disease with an initial focus on osteoarthritis. This drug candidate is a potent senolytic small molecule inhibitor of the MDM2\/p53 protein interaction. Disruption of this protein interaction can trigger the elimination of senescent cells. Our investigational new drug, or IND, application for UBX0101 was cleared by the U.S. Food and Drug Administration, or FDA, in April 2018, and they\u00a0plan to initiate a Phase 1 clinical study in osteoarthritis in the second quarter of 2018. They\u00a0expect to receive data from this clinical study in the first quarter of 2019.<\/p>\n<p><a href=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/04\/Screen-Shot-2018-04-27-at-10.18.33-AM.png\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-4228\" src=\"http:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/04\/Screen-Shot-2018-04-27-at-10.18.33-AM.png\" alt=\"Drugs.UBX\" width=\"668\" height=\"289\" srcset=\"https:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/04\/Screen-Shot-2018-04-27-at-10.18.33-AM.png 668w, https:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/04\/Screen-Shot-2018-04-27-at-10.18.33-AM-600x260.png 600w, https:\/\/www.ipoboutique.com\/blog\/wp-content\/uploads\/2018\/04\/Screen-Shot-2018-04-27-at-10.18.33-AM-300x130.png 300w\" sizes=\"(max-width: 668px) 100vw, 668px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Collaborations \/ License Agreements:\u00a0<\/strong>The company has license agreements and\/or collaborations with Ascentage Pharma Group, The Regents of the University of Michigan &amp;The MayoFoundation for Education and Research<\/p>\n<p><center><\/p>\n<div align=\"left\"><\/div>\n<p><\/center><strong>Book-Building Status<\/strong>: The way the book comes together during the week of the roadshow is the most critical indicator to first-day and first-week performance. IPO Boutique uses its 45 years of experience and sources all over the street to gather daily subscription levels, specific price guidance and what type of investors are currently in the book or are anchoring orders in the book. In addition, recent underwriter performance on sector specific deals is a strong factor that IPO Boutique takes into account when determining if our clients should indicate for any offering.<\/p>\n<p><a href=\"https:\/\/www.ipoboutique.com\/Subscribe.html\"><span style=\"font-weight: 400;\">IPO Boutique subscription clients receive daily updates on this critical information.<\/span><\/a><\/p>\n<p><strong>Conclusion<\/strong>: IPO Boutique provides ratings, daily commentary and a forecast for how this IPO will open vs. its offering price. We have kept a\u00a0<a href=\"https:\/\/www.ipoboutique.com\/cgi\/ipo-track-record-summary-report.php\"><span style=\"font-weight: 400;\">track record<\/span><\/a>\u00a0with our performance for last 12 years at our website. Additionally, here&#8217;s a<a href=\"http:\/\/www.ipoboutique.com\/blog\/?p=3655\"> 2017 recap of our performance<\/a>\u00a0to showcase the value of IPO Boutique&#8217;s service.<\/p>\n<p><b>Indicate with confidence,\u00a0<\/b><a href=\"https:\/\/www.ipoboutique.com\/Subscribe.html\"><b>SUBSCRIBE<\/b><\/a><b>\u00a0today.<\/b><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Company: Unity Biotechnology, Inc. Symbol: UBX Description: They are looking to develop a broad portfolio of drug candidates to treat the diseases of aging, and they plan to initiate their first clinical study of their lead drug candidate in the first half of 2018. Trade Date: 5\/3 Shares: 5 million Price Range: $16.00-$18.00 Underwriter(s): Goldman[&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"zakra_general_container_width":0,"zakra_general_content_width":0,"zakra_general_sidebar_width":0,"zakra_sticky_header":"customizer","zakra_header_main_area":true,"zakra_site_logo_width":0,"zakra_header_top_enabled":"customizer","zakra_header_top_style":"customizer","zakra_primary_menu_item_style":"customizer","zakra_page_header_text_color":"","zakra_page_header_layout":"customizer","zakra_page_title_bg":"","zakra_footer_widgets_bg_image":0,"zakra_page_title_bg_repeat":"customizer","zakra_page_title_bg_position":"customizer","zakra_page_title_bg_size":"customizer","zakra_page_title_bg_attachment":"customizer","zakra_breadcrumbs_enabled":"customizer","zakra_breadcrumbs_text_color":"","zakra_breadcrumbs_separator_color":"","zakra_breadcrumbs_link_color":"","zakra_breadcrumbs_link_hover_color":"","zakra_page_title_bg_image":0,"zakra_footer_widgets_enabled":"customizer","zakra_footer_column_layout_1_style":"customizer","zakra_footer_widgets_bg":"","zakra_footer_widgets_bg_repeat":"customizer","zakra_footer_widgets_bg_position":"customizer","zakra_footer_widgets_bg_size":"customizer","zakra_footer_widgets_bg_attachment":"customizer","zakra_footer_bar_enabled":"customizer","zakra_footer_bar_style":"customizer","footnotes":""},"categories":[24],"tags":[],"class_list":["post-4226","post","type-post","status-publish","format-standard","hentry","category-ipo"],"_links":{"self":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts\/4226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/comments?post=4226"}],"version-history":[{"count":1,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts\/4226\/revisions"}],"predecessor-version":[{"id":4229,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/posts\/4226\/revisions\/4229"}],"wp:attachment":[{"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/media?parent=4226"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/categories?post=4226"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ipoboutique.com\/blog\/wp-json\/wp\/v2\/tags?post=4226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}